Search on: TRANSFORMING GROWTH FACTOR ALPHA 
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Descriptor English:   Transforming Growth Factor alpha 
Descriptor Spanish:   Factor Transformador de Crecimiento alfa 
Descriptor Portuguese:   Fator Transformador de Crescimento alfa 
Synonyms English:   Epidermal Growth Factor-Related Transforming Growth Factor
TGF-alpha  
Tree Number:   D12.644.276.960.700
D12.776.467.960.700
D23.529.960.700
Definition English:   Factor isolated in a variety of tissues including epithelium, and maternal decidua. It is closely related to EPIDERMAL GROWTH FACTOR and binds to the EGF receptor. TGF-alpha acts synergistically with TGF-beta in inducing phenotypic transformation, but its physiological role is unknown. 
History Note English:   91; was see TRANSFORMING GROWTH FACTORS 1989-90; TGF-ALPHA was see TRANSFORMING GROWTH FACTORS 1989-90 
Allowable Qualifiers English:  
administration & dosage adverse effects
agonists antagonists & inhibitors
analysis biosynthesis
blood cerebrospinal fluid
chemistry classification
chemical synthesis contraindications
drug effects deficiency
diagnostic use economics
genetics history
immunology isolation & purification
metabolism pharmacology
physiology pharmacokinetics
poisoning radiation effects
supply & distribution secretion
standards toxicity
therapeutic use urine
Record Number:   29138 
Unique Identifier:   D016211 

Occurrence in VHL:
 

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